Familial antithrombin III deficiency andM pneumoniae pneumonia
نویسندگان
چکیده
deficiency' and reflects the importance of this serine protease inhibitor for the anticoagulant activity of heparin. Our experience shows the importance of screening for an underlying disorder in the young with thrombosis and strongly suggests that prophylactic measures aimed at preventing thrombosis should be considered in acutely ill subjects with infection and familial thrombophilia. 1 Rosenberg RD. Actions and interactions of antithrombin and heparin. N Engl J Med 1975;292:146-51. 2 Odegard OR, Abildgaard U. Antithrombin III: Critical review of assay methods. Significance of variations in health and disease. Haemostasis 1978;7:127-34. 3 Lechner K, Thaler E, Niessner H, Nowotny C, Portsch H. Antithrombin III mangel und thromboseneigung. Wien Klin Wochenschr 1977;89:215-22. 4 Egeberg 0. Inherited antithrombin deficiency causing thrombophilia. Thromb Diath Haem 1965;13:516-30. 5 Hirsch J. Congenital antithrombin III deficiency. AmJMed 1989;87(suppl 3B):34-8. 6 Filip DJ, Eckstein JD, Veltkamp JJ. Hereditary antithrombin III deficiency and thromboembolic disease. Am J Hematol 1976;2:343-9.
منابع مشابه
Familial antithrombin III deficiency and Mycoplasma pneumoniae pneumonia.
A 10 year old girl presented with a massive femoral vein thrombosis associated with Mycoplasma pneumoniae pneumonia. Subsequently type I familial antithrombin III deficiency was diagnosed. It is suggested that prophylactic measures aimed at preventing thrombosis should be considered in acutely ill subjects with infection and familial thrombophilia.
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